Aug. 2017 – Present
Professor, Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan
Principal investigator
Professor
Chien-Chong Hong
Education
- Ph. D. in Electrical Engineering - University of Cincinnati, Cincinnati, Ohio, USA, 2004
- M.S. in Electrical Engineering - University of Cincinnati, Cincinnati, Ohio, USA, 2001
- M.S. in Mechanical Engineering - National Taiwan University, Taiwan, 1995
- B.S. in Mechanical Engineering - National Cheng Kung University, Taiwan, 1993
Experience
Aug. 2012 – July 2017
Associate Professor, Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan
Aug. 2006 – July 2012
Assistant Professor, Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan
June 2005 – May 2006
Adjunct Assistant Professor, Department of Bioengineering, Clemson University, USA
Nov. 2004 – Oct. 2005
Post-Doctoral Fellow, Proteomics Center, Medical University of South Carolina, USA
Research
Biomedical microsystems that bring micro/nanofabrication, biosensing and computation together — from smart-polymer and nanostructure engineering to AI-assisted cellular and molecular analysis.
Current directions (2021–present)
- AI-assisted biomedical signal and image analysis — transformer models for early identification of bacteremia from hematology-analyzer impedance data; multitask learning for ultrasound segmentation and classification
- Cellular electrical phenotyping — tip-focused dielectrophoresis, impedance cytometry and microfluidic flow cytometry for cell viability and single-cell discrimination
- Nanopore sequencing and AI basecalling — decoding DNA sequences from ionic-current signals, extended to single-bacteria and single-cell electrical detection
- Quantum dot–based multimodal biosensing — cross-checking fluorescence and electrochemical readouts on one chip
- Organ-on-a-chip with integrated sensing and control — placenta-on-a-chip and tissue-barrier models under controlled flow and shear stress
- Intelligent biosensing and point-of-care systems — FPGA edge computing, label-free electrochemical biochips, fingertip-blood testing
Established platforms (2006–2020)
- Molecularly imprinted polymers and artificial recognition elements for label-free biosensing
- Smart polymers — shape-memory, conducting and piezoelectric polymers for on-chip actuation, vacuum generation and ultrasonic transduction
- Micro/nanofabrication — nanoimprinted piezoelectric nanograss, sub-20 nm polymer nanotip and nanopore arrays
- Microfluidic biochips and lab-on-a-chip — plasma separation, droplet generation, passive mixing and on-chip fluid driving
- Printed and flexible electronics — material inkjet printing and roll-printed silver-nanowire transparent conductive electrodes
- Breath sensing and nanobio interfacing — on-tube nanowire sensor arrays for exhaled-breath biomarkers, nanobioelectronics
Publications
IHIT-BED: an interpretable transformer approach using unbiased hematology analyzer impedance data for early identification of bacteremia in emergency department
Bioinformatics Advances · IF 2.6 · 6(1), vbaf322 · 2026 · DOI: 10.1093/bioadv/vbaf322
Multitask learning for ultrasound image classification and segmentation of endometrium in the diagnosis of ectopic pregnancy
Taiwanese Journal of Obstetrics & Gynecology · IF 2.7 · 65, 952–960 · 2026 · DOI: 10.1016/j.tjog.2026.05.006
Roller-Induced Bundling of Long Silver Nanowire Networks for Strong Interfacial Adhesion, Highly Flexible, Transparent Conductive Electrodes
Scientific Reports · IF 4.9 · 2017
Handheld Analyzer with Molecularly-Imprinted Biosensors for Electrical Detection of Anesthetic Propofol in Plasma Samples
Biosensors and Bioelectronics · IF 11.8 · 2016
A Disposable Breath Sensing Tube with On-Tube Single-Nanowire Sensor Array for On-Site Detection of Exhaled Breath Biomarkers
Lab on a Chip · IF 6.3 · 2016
Easy-to-Attach Vacuum Modules for Droplets Generation from Small Sample Volumes
Microfluidics and Nanofluidics · IF 2.9 · 2016
Electrodeposition of Piezoelectric Polymer Ultrasonic Transceivers for On-Chip Antibiotic Biosensors
Journal of the Electrochemical Society · IF 3.5 · 2016
Bendable Transparent Conductive Meshes Based on Multi-Layer Inkjet-Printed Silver Patterns
Journal of Micromechanics and Microengineering · IF 2.5 · 2016
Self-Regenerating Photocatalytic Sensor Based on Dielectrophoretically-Assembled TiO2 Nanowires for Chemical Vapor Sensing
Sensors and Actuators B: Chemical · IF 8.3 · 2014
Fabricating High-Resolution Offset Color-Filter Black Matrix by Integrating Heterostructured Substrate with Inkjet Printing
Journal of Micromechanics and Microengineering · IF 2.5 · 2014
Point-of-Care Protein Sensing Platform based on Immuno-Like Membrane with Molecularly-Aligned Nanocavities
Biosensors & Bioelectronics · IF 11.8 · 2013
Enhanced Piezoelectricity of Nanoimprinted Sub-20-nm Poly(vinylidene fluoride-trifluoroethylene) Copolymer Nanograss
Macromolecules · IF 5.7 · 2012
Enhanced Anesthetic Propofol Biochips by Modifying Molecularly Imprinted Nanocavities of Biosensors
Biomedical Microdevices · IF 4.4 · 2012
次20奈米可撓性壓電高分子奈米草觸壓感測器
微系統暨奈米科技協會會刊, 第28期, 第27-31頁 · 2012
A Microfluidic Chip Platform with Electrochemical Carbon Nanotube Electrodes for Preclinical Evaluation of Drug Release Profile of Antibiotic Nanocapsules
Biosensors & Bioelectronics · IF 11.8 · 2011
Pre-Programmable Polymer Transformers as On-Chip Microfluidic Vacuum Generators
Microfluidics and Nanofluidics · IF 2.9 · 2011
奈米結構材料與奈米生醫機電系統之發展
台灣奈米會刊, 第26期, 第38-51頁 · 2011
Fabrication of Morphology-Controlled Sub-20 nm Polymer Nanotip and Nanopore Arrays Using an Identical Nanograss Mold
Macromolecules · IF 5.7 · 2010
A Disposable Microfluidic Biochip with On-Chip Molecularly Imprinted Biosensors for Optical Detection of Anesthetic Propofol
Biosensors & Bioelectronics · IF 11.8 · 2010
Development of Functional Lab-on-a-Chip on Polymer for Point-of-Care Testing of Metabolic Parameters
Lab on a Chip · IF 6.3 · 2008
An On-Chip Air-Bursting Detonator for Driving Fluids on Disposable Lab-on-a-Chip Systems
Journal of Micromechanics and Microengineering · IF 2.5 · 2007
A Novel In-Plane Passive Microfluidic Mixer with Modified Tesla Structures
Lab on a Chip · IF 6.3 · 2004
A Functional On-Chip Pressure Generator Using Solid Chemical Propellant for Disposable Lab-on-a-Chip
Lab on a Chip · IF 6.3 · 2003
Proposal Reviewer
- Proposal Funding Reviewer, USA National Science Foundation –IRFP (International Research Fellowship Program)
- Proposal Funding Reviewer, Industrial Technology Research Institute (ITRI), Taiwan
- Proposal Funding Reviewer, Taiwan National Science Council
Journal Reviewer
- Advanced Materials
- Biosensors & Bioelectronics
- Journal of Microelectromechanical Systems
- Microfluidics and Nanofluidics
- Journal of Materials Chemistry
- Journal of Micromechanics and Microengineering
- Lab on a Chip
- Nanoscale
- Polymer International
- Journal of Biochips and Tissue Chips
- Polymer Chemistry
- Applied Mathematical Modelling
- Electrophoresis
- Electroanalysis
- Journal of Electroanalytical Chemistry
- Journal of the Chinese Institute of Engineers
- IEEE Sensors Journal
- RSC Advances
- Analytica Chimica Acta
- Analyst
- International Journal of Nanomedicine
- Nanobiosensors in Disease Diagnosis
- Analytical Methods
- ACS Nano
- ACS Applied Materials & Interfaces
- Thin Solid Films
- Microelectronic Engineering
- Micromachines
- PLOS ONE
- Scientific Reports
Conference Reviewer
- IEEE Sensors Conference 2018
- ASME IMECE Congress
- IEEE International Conference on Robotics and Biomimetics
- Symposium on Nano Device Technology
- SEMBA
- 醫工年會論文
- 自動化科技研討會2012
- 中國機械工程學會論文2012
Professional Service
- Associate Editor, Journal of Microelectronic Engineering
- Associate Editor, Micro and Nano Engineering
- Editorial Board, Journal of Biochips and Tissue Chips
- International Conference Session Chair, 2010 International Conference on Advanced Manufacture
- SEMBA 2012 Session Chair
Awards
- Our sub-20 nm polymer nanotip/nanopore research was selected by Nature Asia Materials for highlighting (2010).
- Our sub-20 nm polymer nanotip/nanopore research was selected by Taiwan National Science Council for highlighting (2010).
- Innovation and Creation Award (NSC Undergraduate Student Research Project), Taiwan National Science Council (2011)
- Teaching Excellence Award, National Tsing Hua University (2011)
- HIWIN Thesis Award — 9th HIWIN Master's Thesis Award, Bronze Medal (2013)
- The 11th National Innovation Award in the Academic Research Category by the Institute for Biotechnology and Medicine Industry (2014)
- Gold Medal, Taipei International Invention Show & Technomart (2015)
- The 15th National Innovation Award in the Academic Research Category by the Institute for Biotechnology and Medicine Industry (2018)
- Outstanding Entrepreneurship Award (First Prize), FITI (From IP to IPO) Program, Ministry of Science and Technology — selected from 126 entrant teams and 15 finalists; NT$2,000,000 (2019)
- Future Tech Breakthrough Award, 2019 Future Tech Expo (FUTEX), Ministry of Science and Technology (2019)
- The 19th National Innovation Award, Startup Enterprise Category (Innovative Medical Devices and Diagnostics), Institute for Biotechnology and Medicine Industry — received by the NTHU spin-off 豐康微流體晶片股份有限公司 together with the clinical team of Chang Gung Memorial Hospital, for the CoreTest-AKI point-of-care testing system (2022)